Dr. K. Ramalingam
Mediclone Biotech Research Center, Chennai, IndiaPresentation Title:
Desynchronizing the molecular events to treat breast cancer
Abstract
It is known that in breast cancer, consequent to the transformation of a normal cell into a cancer/malignant cell, the latter acquires innumerable potentials to continue its survival inside the body of the patient, making her to succumb to the severity of the disease and end up in death. Cancer cells odyssey involves synchronization of multifarious molecular events by the two-way operations of genes expression and suppression.
As for breast cancer the genomic players like BRCA 1, BRCA 2, MSH, TP53 and their mutations have been well established. In addition, several growth factors and/or proteins are synthesized synchronously to fulfil the journey of cancer cells phases viz., 1st, 2nd, 3rd and 4th. By desynchronization of the successive events the breast cancer and its recurrence which is detrimental to the patient can be eliminated.
The whole strategies right from prevention up to maintenance after treatment and after remission period involve the prevention, diagnosis, chemotherapy, radiotherapy and surgery. Alongside the above, complimentary nutritional, metabolic and pleiotropic generic medicinal therapy can outsmart the detrimental resistant cancer cells.
As for breast cancer the genomic players like BRCA 1, BRCA 2, MSH, TP53 and their mutations have been well established. In addition, several growth factors and/or proteins are synthesized synchronously to fulfil the journey of cancer cells phases viz., 1st, 2nd, 3rd and 4th. By desynchronization of the successive events the breast cancer and its recurrence which is detrimental to the patient can be eliminated.
The whole strategies right from prevention up to maintenance after treatment and after remission period involve the prevention, diagnosis, chemotherapy, radiotherapy and surgery. Alongside the above, complimentary nutritional, metabolic and pleiotropic generic medicinal therapy can outsmart the detrimental resistant cancer cells.
Biography
Dr. K. Ramalingam served 28 years as Professor of Zoology and Biotechnology and as Senior Scientist at Mediclone Biotech Co. He also held the positions of Head of the Department and Dean of Science at AMET University, Chennai. In addition, he was a member of the Institutional Internal Ethics Committee at Dr. Rai Memorial Cancer Hospital, Chennai. He is presently working as Honorary Senior Project Scientist at Chennai Snake Park Trust.